HEPTRAL 500MG (20S - BOX)

HEPTRAL 500MG (20S - BOX)

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RM140.90
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RM140.90
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Description
Each enteric-coated tablet contains ademetionine 949 mg equivalent to 500 mg ion. It also contains the following excipients: Microcrystalline cellulose, magnesium stearate, polyethylene glycol 6000, polymethacrillates, polysorbates, colloidal silica, emulsified silicon, sodium-starch glycolate, talc.
Ademetionine is (sulfo-adenosyl-L-methionine)1,4-butanedisulfonate.
Indications/Uses
Treatment of adults with intrahepatic cholestasis in precirrhotic and cirrhotic states, and intrahepatic cholestasis in pregnancy.
Dosage/Direction for Use
Treatment can be initiated with parenteral administration and continued or initiated orally.
Adults: Intrahepatic Cholestasis: 10-25 mg/kg/day orally. Usual Starting Dose: 800 mg/day. Total Daily Dose: Not to exceed 1600 mg.
Maintenance Therapy: 800-1600 mg/day.
Administration: Ademetionine tablets should be swallowed whole and not chewed.
For better absorption of ademetionine and complete therapeutic effect, ademetionine tablets should not be taken with meals.
Overdosage
Cases of overdose with ademetionine appear to be rare. Physicians should contact local poison control centers. In general, patients should be monitored and supportive care provided.
Contraindications
Known hypersensitivity to ademetionine or to any of the excipients of Heptral.

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